TYLENOL® with Codeine exposes people and various end users on the pitfalls of opioid addiction, abuse and misuse, which can lead to overdose and Dying.promethazine boosts effects of daxibotulinumtoxinA by pharmacodynamic synergism. Use Warning/Watch. Drugs with anticholinergic effects could potentiate botulinum toxin effects, which may result in e